Become A Member

Introduction: Non-communicable diseases (NCDs) such as diabetes, cardiovascular diseases, obesity, and hypertension pose a major global health burden. Panchakarma, a cornerstone of Ayurveda, encompasses detoxification and rejuvenation therapies with potential preventive and therapeutic benefits for NCDs. Understanding its role in integrative health approaches is crucial. Methods: A systematic literature review was conducted using PubMed, Scopus, Web of Science, Google Scholar, and classical Ayurvedic texts including Charaka Samhita, Sushruta Samhita, and Ashtanga Hridaya. Studies included randomized controlled trials, observational studies, systematic reviews, meta-analyses, and authoritative Ayurvedic literature addressing Panchakarma and NCDs. Exclusion criteria encompassed non-peer-reviewed publications, case reports, and studies with insufficient methodological rigor. Results: Evidence suggests that Panchakarma interventions, including Virechana, Basti, Abhyanga, and Nasya, improve metabolic regulation, cardiovascular health, glycemic control, stress reduction, and immune modulation. Clinical trials report reductions in BMI, blood glucose, lipid profiles, and blood pressure, along with improved psychosomatic well-being. Integration with lifestyle modifications and Yoga further enhances preventive and therapeutic outcomes. Discussion: Panchakarma offers a mechanistic framework for managing NCDs, aligning with modern preventive medicine principles. However, research is limited by heterogeneity in protocols, small sample sizes, and variable outcome measures. Standardized procedures, long-term follow-up, and biomarker-based assessments are required to validate its efficacy in integrative care.

KEYWORDS: Ayurveda, Integrative Medicine, Non-Communicable Diseases, Panchakarma, Preventive Health